Main Street Pizza & Cafe Menu (2025 Update)
Welcome to Main Street Pizza & Cafe, a charming culinary gem located at 2540 Main St, Irvine, CA. This delightful eatery is renowned for its delectable offerings, from fresh bagels served with creamy spreads to indulgent hot sandwiches that promise to satisfy any craving.
What truly stands out are the pizzas, celebrated for their rich sauces and quality toppings. Customers rave about the Chicken Pesto Panini, identified as a must-try, while the lasagna has garnered widespread acclaim, leaving eager diners asking about its origins. The friendly and accommodating staff enhances the dining experience, making it feel like family.
Complement your meal with one of their refreshing smoothies, available in delightful flavor combinations such as Morning Glory and Raspberry Royal. Whether you're a local or just passing through, Main Street Pizza & Cafe is an unforgettable stop for delicious food and genuine hospitality.
Breakfast Sandwiches
Vegetarian Panini
Spinach, tomato, roasted red peppers, egg, cheddar cheese and pesto sauce on Sourdough bread.
Fruit Parfait
Vegetarian Burritos
Potato, avocado, egg, pico de gallo and cheese with homemade salsa.
Fruit Medley
Open Faced Smoked Salmon Bagel Sandwich
Bagel, smoked salmon, fresh dill, cucumber, cream cheese and capers.
Breakfast Panini
Choice of bacon, ham or sausage with egg and cheese on Sourdiugh bread
Hot Oatmeal
Topped with walnuts, almonds, chia seeds, brown sugar, raisins and cinnamon.
Breakfast Burritos
Choice of bacon, sausage, chorizo or ham with egg, roasted potato, and cheese, comes with homemade salsa.
Bagel Sandwich
Choice of bacon, ham or sausage with egg and cheese.
Pasta & Salad
Pasta
Hot Pastas
Lasagna
Six layers of pasta joined by our delicious marinara sauce topped with mozzarella cheese.
Ravioli
Cheese or spinach. Choice of marinara, meat, Alfredo, Roasted Red pepper or pesto sauce.
Cajun Pasta
Fettuccini pasta and chicken breast in a spicy cajun cream sauce.
Fettuccini Alfredo
Fettuccini smothered in our delicious alfredo sauce.
Jumbo Cheese Ravioli With Roasted Red Pepper Cream Sauce
Cheese ravioli, mushrooms, fresh garlic, and roasted red pepper sauce.
Pick A Pasta & Sauce
Spaghetti Or Penne With Meatballs
Served with our homemade meat sauce and meatballs.
Baked Chicken Penne
Penne pasta with shredded chicken breast, mozzarella cheese, and marinara sauce.
Linguini & Shrimp
Shrimp, mushrooms, green peppers and fresh garlic with red or white sauce.
Chicken Breast Parmigiana
Tender breaded chicken topped with mozzarella and Parmesan cheese. Served with spaghetti in marinara.
Spaghetti With Sausage & Meat Sauce
Almond Chicken Side Salad
Roasted chicken, celery, red onion, almonds, raisins, green apple, and mayo, perched on organic mixed greens.
Homemade Tuna Side Salad
Tuna, finely minced fresh veggies and herbs, lemon juice, mayo and dijon mustard, perched on organic mixed greens.
Garden Salad Side Salad
Organic mixed greens, romaine lettuce, carrots, red cabbage, grape tomatoes, cucumber, and bell peppers.
Side Salads
Soft Drinks & Juice
Apple Juice
Cranberry Juice
Bottled Coke Products
The cold, refreshing, sparkling classic that America loves.
2 Liter
Snapple
Bottled Water
Canned
Fountain
Fresh Squeezed Orange Juice
Sausage
Mozzarella cheese with sausage links.
Chicken Parmesan
Tender breaded chicken with marinara sauce and mozzarella cheese.
Meatball & Cheese
Meatballs served with our meat sauce and mozzarella cheese.
Hot Sandwiches
Paninis
Turkey & Bacon Panini
Turkey, bacon, tomato, Gouda cheese, and herb aioli.
Chicken Pesto Panini
Roasted chicken, provolone cheese, baby spinach, sun-dried tomato, and basil pesto served on sourdough bread.
Veggie Panini
Grilled zucchini and peppers, onion, avocado, tomato, muenster cheese and pesto sauce.
Tiramisu
Cheesecake
Desserts
Wraps
Turkey Bacon & Avocado Wrap
Sliced turkey breast, bacon and swiss cheese with mayo, mustard, avocado, lettuce and tomato on a flour tortilla.
Tuna Wrap
Tuna salad and mixed greens, sliced tomato, cucumber, and havarti cheese on a spinach tortilla.
Chicken Caesar Wrap
Grilled chicken, romaine hearts, tomato, Parmesan cheese and caesar dressing on a wheat tortilla.
Veggie Wrap
Avocado, havarti, and feta cheese, cucumber, roasted red peppers, lettuce, spinach, tomato, onion and pesto sauce on a wheat tortilla.
Chicken Pesto Wrap
Grilled chicken, provolone cheese, roasted red peppers, pesto sauce, lettuce and tomato with vinaigrette on a flour tortilla.
Almond Chicken Salad Wrap
homemade chicken salad with lettuce and tomato on a flour tortilla.
Medium Cheese Pizza (13")
Large Cheese Pizza (16")
XL Cheese Pizza (18")
Small Cheese Pizza (10")
Pizza
Appetizers
Buffalo Wings Half Dz
Buffalo Wings Full Dz
French Fries
Garlic Bread
Order of five.
Chai Latte Medium
Cappuccino Medium
Hot Cocoa Medium
Hazelnut Latte Medium
Cafe Latte Medium
Cafe Mocha Medium
Vanilla Latte Medium
Caramel Latte Medium
Specialty Drinks
Protein Shakes
Banana Peach
Peaches, banana and protein.
Orange Strawberry
Orange juice, strawberries and protein.
Vanilla Latte
Caramel Latte
Hazelnut Latte
Mocha
Latte
Blended Drinks
Specialty Pizzas
Italian Meatball
Pizza sauce, sliced meatball, fresh basil and oregano, topped with grape tomatoes and Parmesan cheese.
Garlic Chicken With White Sauce
Alfredo sauce, fresh garlic, grilled chicken and bacon bits.
Meat Lovers
Pepperoni, sausage, ham, salami, ground beef, and bacon.
Artichoke Feta
Artichoke hearts, tomato, roasted garlic, feta and mozzarella cheese with basil pesto or red pizza sauce.
The Works
Pepperoni, ham, sausage, salami, green peppers, onions, mushrooms, fresh tomato, and olives.
Garlic Chicken
Roasted garlic, grilled chicken breast, fresh mushrooms, and mozzarella cheese.
Greek Style Pizza
Pizza sauce, mozzarella cheese, sun dried tomatoes, spinach, kalamata olives, feta cheese.
Chunky BBQ Chicken
Oven-roasted chicken, barbecue sauce, red onions, gouda, blue cheese crumbs, and mozzarella cheese, roasted red pepper and cilantro.
Hawaiian
Ham and pineapple.
Vegetarian
Green peppers, onions, olives, mushrooms, and tomato.
Margherita
Fresh roma tomato slices and fresh basil topped with mozzarella and Parmesan cheese.
Stromboli
Mozzarella and Ricotta cheese with ham, pepperoni, Italian sausage and salami.
Spinach & Artichoke
Mozzarella and Ricotta cheese with spinach, artichokes, and feta cheese.
Pepperoni Or Sausage
Mozzarella and ricotta cheese with choice of pepperoni or sausage.
Calzones
Smoothies
The Maui
Pina colada and strawberries.
Razzle Dazzle
Raspberries, banana and orange juice.
Strawberry Splash
Banana and strawberries.
Raspberry Royal
Raspberries and banana.
Morning Glory
Peaches and banana.
Apple Walnut Salad
Organic mixed greens, green apple, caramelized walnuts, blue cheese, raisins, berries with our balsamic vinaigrette.
South Of The Border
Crisp romaine lettuce, avocado, cilantro, corn salsa, and cheddar cheese topped with tortilla strips with pepita dressing.
Antipasto Salad
Romaine's hearts topped with mortadella, salami, ham, kalamata olives, grape tomatoes, peppers, pepperoncini, cucumbers, cheddar, and mozzarella cheese with vinaigrette.
Quinoa Jicama Salad
Organic mixed greens, red onion, avocado, cilantro, tomato, raisins, jicama, pumpkin seed, cotija cheese and quinoa with mango lime vinaigrette dressing.
California Salad
Romaine lettuce with grilled chicken, avocado, grape tomato, blue cheese crumbles and cheddar cheese with choice of ranch or champagne white vinaigrette.
Chinese Chicken Salad
Organic mixed greens, crisp romaine, chicken, fresh mandarins, peppers, carrots, cilantro, toasted almonds and sesame seeds topped with crisp wontons, served with ginger sesame dressing.
Caesar Salad
Crisp romaine hearts lettuce and Parmesan cheese with caesar dressing.
Beet Salad
Organic mixed greens, oven-baked beets, caramelized walnuts, goat cheese, berries with tarragon red wine vinaigrette dressing.
Chipotle Chicken Salad
Organic mixed greens, romaine, grilled chicken, roasted tricolored peppers, red onion, corn, tomato, fresh cilantro, avocado, and cheddar cheese with cilantro chipotle dressing.
BBQ Chicken Salad
Grilled chicken with barbecue sauce, lettuce, roasted corn, cilantro, peppers, red cabbage, carrots, pineapple and mozzarella, topped with crispy tortilla strips, served with ranch dressing.
Salads
Bagels & Cream Cheese
Bagels
Bagel & Cream Cheese
4oz Cream Cheese
Chicken Pesto
Roasted chicken, provolone cheese, basil pesto sauce lettuce, tomato and vinaigrette on a baguette.
Ham & Cheese
Sliced ham and Havarti cheese with herb aioli, lettuce, and tomato on rye or marble rye bread.
Sicilian Sandwich
Mortadella, salami, roasted red peppers, red onion, chopped pepperoncini, provolone cheese, lettuce and tomato with our homemade roasted pepper sauce on a baguette.
Roast Beef Sandwich
Roast beef, pepper jack cheese, lettuce, tomato and horseradish spread on ciabatta bread.
Almond Chicken Salad Sandwich
Tasty homemade chicken with lettuce and tomato.
Vegetarian Sandwich
Avocado, havarti, and feta cheese, cucumber, spinach, roasted red peppers, lettuce, tomato, onion and pesto sauce on wheat bread.
Turkey Swiss
Turkey breast, swiss cheese, lettuce and tomato with herb aioli on wheat or ciabatta.
Tuna Salad Sandwich
Tasty homemade Tuna salad with Sliced Cucumbers and Havarti Cheese with Spring Mix and tomato.
Moroccan Sandwich
Turkey, Roasted Red peppers and Red Onion, Arugula, Tomato & Avocado with Chermula sauce.